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Conversely, rare non-functioning mutations in ALPL cause a genetic condition called hypophosphatasia, which in addition to high levels of pyrophosphate, causes high levels of P5P.[ref] Peripheral Neuropathy and Vitamin B6: Vitamin B6 deficiency is one of the more common causes of peripheral neuropathy.[ref][ref] On the other hand, excess consumption of vitamin B6 supplements for longer periods (months to years) has caused neuropathy or movement disorders in a few individuals

[DOI] [PMC free article] [PubMed] [Google Scholar] Liu J

Epithalon vs NAD+ NAD+ supports mitochondrial energy

Ruy F, Vercesi AE, Kowaltowski AJ: Inhibition of specific electron transport pathways leads to oxidative stress and decreased Candida albicans proliferation