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Figure S7 Healthcare costs Figure S8 (a-f) Funnel plots Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made

Duration of Use : Many experts suggest starting with higher doses for 6-12 weeks before moving to a maintenance dose to replenish the body's levels effectively

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This historical record is a warning against both wishful thinking and cynicism