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10.1016/S1054-3589(10)58005-0 189 TianJ.DangH.WallnerM.OlsenR.KaufmanD

Because secretagogues amplify natural GH pulses rather than creating a pharmacokinetic peak from outside, dosing in the evening (near sleep onset) aligns the induced pulse with the body's largest natural nocturnal GH surge

J Neurosci 21:41834187 Ran Q, Van Remmen H, Gu M, Qi W, Roberts LJ, Prolla T, Richardson A (2003) Embryonic fibroblasts from Gpx4+/ mice: a novel model for studying the role of membrane peroxidation in biological processes