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A phase 2a trial in patients with trigeminal neuralgia, vixotrigine may provide a potential treatment option, although it did not show a statistically significant advantage

Superoxide free radical rapidly is converted chemically or enzymatically by superoxide dismutase to H 2 O 2 , which in the presence of Cu + leads to production of the highly reactive hydroxyl free radical that is highly capable of initiating lipid peroxidation (1, 8)