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This triple mechanism produces synergistic effects on appetite suppression, energy expenditure, and glucose metabolism that exceed single or dual agonists

For instance, N-acetylcysteine (NAC), a precursor to GSH, has shown promise in increasing brain GSH levels and improving symptoms in first episode psychosis patients. NAC is so medically effective that it has been classified a medicine, hence not a food, and is no longer available over the counter in the US

Sample size Sample size was determined according to the phase 2 crossover part of the DIVE-1 study

10.1021/acsnano.9b08658 76 HaqueE.WardA

It has also high levels of flavokavain B, leading to a higher probability of hepatotoxicity [28]