a boy with c major lips Frontal (top A, B, C) and profile (bottom D, E, F) photographs of NEW C-BL! Adapted from the

Data availability The datasets used and/or analyzed during the current study are available at Zenodo: Abbreviations ALS: Amyotrophic lateral sclerosis epSPCs: Ependymal stem progenitor cells SOD1: Superoxide dismutase 1 HIF: Hypoxia-inducible factor PLGA: Poly-lactide-co-glycolide NPs: Nanoparticles DCM: Dichlorometane DLS: Dynamic light scattering DMSO: Dimethyl sulfoxide PCA: Principal component analysis TCA: Tricarboxylic acid PPP: Pentose phosphate pathway EAAT2: Excitatory amino acid transporter 2 References Feldman, E

10.1038/s41416-018-0327-z 45 GoebelG.BergerR.StrasakA

Ashwagandha is typically used at 300 to 600mg of a standardized root extract daily, taken with a meal for absorption, with 300mg twice daily the dose used in the most well-controlled trials showing cortisol reduction

Emergency treatment involves oxygen therapy, intravenous fluids, and monitoring of vital signs to stabilize the individual

S., Zhang, D