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Silybin showed higher cytotoxic, antiproliferative, and anti-inflammatory activities in the CaCo cancer cell line while retaining viability and proliferation in normal intestinal IPEC-1 cells

Selenium is also an essential component of other metabolic systems that deal with oxidative stress, such as the thioredoxin system

Notably, all these studies are preclinical and involve experimental animal models, encompassing diverse pathways and targets

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