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doi: 10.1371/journal.pone.0129813 138 MokASolomonONayakRRCoitPQuachHLNitithamJet al

We obtained a total of seven major groups of cells, which were dopaminergic neurons, non-dopaminergic neurons, astrocytes, oligodendrocytes, OPCs, endothelial cells/pericytes and microglia/macrophages

Pentoxifylline attenuates tubulointerstitial fibrosis by blocking Smad3/4-activated transcription and profibrogenic effects of connective tissue growth factor

Under normoxic conditions, HIF-1 is degraded via the ubiquitination pathway mediated by proteins such as prolyl hydroxylase domain (PHD) enzymes and the von HippelLindau (VHL) tumor suppressor protein