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Initial results from the northstar study (HGB-204): a phase 1/2 study of gene therapy for -thalassemia major via transplantation of autologous hematopoietic stem cells transduced ex vivo with a lentiviral A-T87Q-globin vector (LentiGlobin BB305 drug product) [abstract] Blood

The relative abundance of Erysipelatoclostridium was increased in vehicle-treated mice that underwent the WD to LD switch (WD/LD-V) relative to the two control groups (LD/LD-V and WD/WD-V) but was not increased in 5A-1MQ-treated mice that underwent the same diet switch (WD/LD-T)