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Oral medications can be at the mercy of the digestive system, and the absorption of oral medications may be hindered by other drugs or medical conditions

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Use of a prodrug can result in improved pharmacokinetics, which can increase a medications effective half-life from hours to days or weeks, thus lengthening the interval during which plasma drug concentrations remain at a relevant level for clinical efficacy

importantly, this action appears to be mediated by ROS/RNS 24