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Description

However, cancer cells then mount an anti-oxidant response that decreases the efficacy of the oxidative component of tamoxifen therapy

Conclusion Our results indicate that repeated treatment of the U87 MG cell line with a combination of 5-Fu, cisplatin, and paclitaxel induces cross-resistance, causing MDR against other chemotherapeutic agents that are distinctly different in terms of chemical structure and mechanism of action