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Description

Our results support the consideration of mitapivat as a potential new therapeutic agent for HS

Pharmacokinetics: Well absorbed from most sites of administration oral tablets for treating dry mouth associated with Sjgrens syndrome eye drops for treating glaucoma, or improving near vision half-life estimates range from 0.76 to 1.35 hours (manufacturer's data) (its a tertiary amine) Crosses the blood brain barrier Drug Interactions: Administered with caution to patients taking beta blockers because of the possibility of cardiac conduction disturbances Notes: Pilocarpine is a natural alkaloid found in South American plants of the genus Pilocarpus