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Description

Barry Conrad Let's have it

Acid hydrolysis of 64 gave (4 S )-4-hydroxy-L-glutamic acid [(2 S ,4 S )- 3 ] as the hydrochloride, however, its enantiomeric purity was not checked

Here, we found that both the single- and double-mismatches completely negated the thermal stabilisation provided by Cu 3 -TC-Py, ruling out metalloinsertion as a potential binding mode