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In fact, elevated propionate production is postulated to be involved in the pathogenesis of ASD, as this SCFA is shown to cross the blood-brain barrier and is able to induce ASD-like behavior in adult rodents, possibly via activation of microglia (177179)

Anxiety-like behavior induced by 6-OHDA animal model of Parkinsons disease May be related to a dysregulation of neurotransmitter systems in brain areas related to anxiety

Mol Biochem Parasitol 159:142145

29 (2 Suppl): S132S142

However, the mechanisms by which fatty liver disease progresses to inflammatory conditions from concomitant obesity and alcohol consumption (here, termed the syndrome of metabolic and alcoholic fatty liver disease (SMAFLD)) are not fully known