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The MAS comprises MDH1/2, GOT1/2, the malate--KG antiporter and the glutamate-aspartate antiporter, which exchanges mitochondrial -KG for cytosolic malate that is synthesized from oxaloacetic acid (OAA) by cytosolic MDH (Fig

Copper is a cofactor for important enzymes, but excessive accumulation can lead to cellular metabolic disorders and death (Zeng et al., 2020

1d,e), with a corresponding increase in PDHc-E2 glutarylation (Fig

This process of detoxification strengthens the body's immune system and helps our bodies better digest and absorb the nutrients in food

It works by inhibiting melanin production, leading to a more even skin tone