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[39] Betaine and performance Research shows that betaine supplementation can increase: Strength [24,25] Power [24,25,34] Body composition [27,28] In one particularly impressive study from 2013, subjects taking 2,500 milligrams of betaine per day the same dose present in these Bodybuilding ELITE Ultimate Pre Workouts led to more than 5 pounds of muscle gain and 6 pounds of fat loss during a one-and-a-half month period

Inhibiting NNMT with 5-amino-1MQ reverses this: NAD+ levels rise, mitochondrial respiration increases, and white adipose tissue (fat storage) shifts toward thermogenesis

The peptidomimetic design often incorporates D-amino acids or non-natural backbones to resist enzymatic breakdown, extending its circulation time in the blood to allow for "homing" to adipose tissue

It can be found in many animal products and fortified foods