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Neuroprotection: Early studies suggest potential cognitive benefits, making it an interesting candidate for Cognitive & Nootropic Research

To learn more about his work and his clinic, as well as to find links to some of the things discussed in today's episode, please see the show note captions

The diterpenoid ester ingenol mebutate (IngMeb) induces cell death causing mitochondrial dysfunction and local inflammatory response

CaP cells depend strongly on the AR NTDs ligand-independent transactivation domain AF1, which mediates also transcriptional activity of agonist- and antagonist-indifferent AR variants after acquired resistance to ADT, but to date cannot be effectively inhibited in clinic [45]