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Description

ISBT Sci Ser

Three small molecules (compounds 1, 2 and 3) previously identified to target Leishmania 16

Apoptosis can be initiated via two major pathways: the intrinsic (mitochondria-dependent) pathway, which is triggered by cellular stress and mitochondrial outer membrane permeabilization, and the extrinsic (death receptor-mediated) pathway, both of which converge on the activation of caspases to execute cell death [53]