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Clean the vial top again with an alcohol swab, draw the additional water in a fresh syringe, and add it slowly down the glass wall

These significantly altered metabolites encompassed diverse classes, including Glycerophospholipids, Fatty Acyls, Prenol lipids, Steroids and steroid derivatives, Carboxylic acids and derivatives, Benzene and substituted derivatives, Phenylpropanoic acids, Benzopyrans, Organooxygen compounds, Glycerolipids, Flavonoids, Phenols, and Sphingolipids

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Moreover, these compounds often induce only transient therapeutic effects, making precise dose control challenging