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Inclusion criteria for participants with MDD required a PHQ-9 score greater than or equal to 15, signifying a moderately-severe to severe depressive mood episode

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However, multiple compounds can theoretically restore NRF2 activity during aging and play a role in telomere maintenance, even in healthy individuals

As animals were obtained in six separate batches due to operational limitations and grouped in cages, the survival curves were plotted using the KaplanMeier method