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In this sense, the aim is to find out whether it is possible to control the cell death process via ferroptosis by means of food or nutritional supplementation

2007;293(2):F5215 Fung TT, Chiuve SE, McCullough ML, Rexrode KM, Logroscino G, Hu FB

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Human data are limited, so its real-world benefits and safety in people are not well established

Therefore, our findings showing that ubiquitylated IL-1, akin to the IL-1 K133A or D129A mutants, is inefficiently cleaved by Caspase-1 raises the interesting possibility that IL-1 K133 ubiquitylation impacts the integrity of the K133:D129 electrostatic interaction to limit caspase-1 processing