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Psychological and neurodevelopmental disorders [edit] In addition to physical manifestations, patients with NF1 are at high risk of developing neurodevelopmental disorders, which result in learning difficulties, attention problems, and other behavioral or social challenges

Oct 2010;76(14):1512-1518

doi: 10.1007/s10753-015-0135-z 61 ChenYFangZMYiXWeiXJiangDS

317 JAK2 over-activation in PASMCs from IPAH patients, promotes IL-6-induced proliferation and migration of PASMCs, thereby elevating PAP and RVH

However, recent technological advances using nanofluidic devices have considerably increased the throughput of this approach 60