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The decrease in mitochondrial energy production can also trigger migraines, Coenzyme Q10 can provide sufficient oxygen and energy to brain cells, improve mitochondrial energy metabolism, and maintain healthy and active brain and nerve cells

This also protects skin elasticity, firmness, and plumpness, which in turn, prevents signs of premature ageing like fine lines

Generally, at the beginning of MASLD development, the expression/activity of antioxidant enzymes usually increases to protect organisms against the increased production of reactive oxygen species

The serine protease matriptase2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin

This work was also funded by the Guangdong Provincial Bureau of Traditional Chinese Medicine (No.20241285) and Guangdong Basic and Applied Basic Research Foundation (No.2022A1515110790 and 2024A1515012478)