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The region's growth formula, which relies heavily on abundant, cheap housing and lax regulation, suddenly had a death toll in the dozens and a price tag in the billions

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doi:10.1016/j.fertnstert.2010.06.027

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However, antigen sampling of luminal microbes is necessary for immunological development, bacterial clearance and the production of IgA, the latter of which is important in restricting microbial adhesion to the mucosal layer and coating commensal species to limit their interaction with immune system (Johansen et al