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Acknowledgments This work was supported by a faculty start-up fund from Pennsylvania State University, and the USDA National Institute of Food and Federal Appropriations under Hatch Project #PEN04938 and Accession #7006507 (F.Z.)

The contribution of reactive astrocytes to neurodegenerative diseases and cognitive impairments is now well established

Since B12 is also essential for fetal development, particularly the development of the neural tube, low B12 can increase the risk of birth defects if left unaddressed in pregnant women

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Thyroid Gland Size and Nodularity : Ultrasound : Imaging to assess thyroid gland size, structure, and presence of nodules