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doi: 10.1016/j.phymed.2021.153894 45 ZongYLiHLiaoPChenLPanYZhengYet al

10.1038/s41584-020-0413-5 116 OdegrdS.FinsetA.MowinckelP.KvienT

The assay involves carefully optimized enzymatic recycling method using glutathione reductase and Ellmans reagent (DTNB)

492 Mutant IDH abnormally accumulates D-2-hydroxyglutarate (D-2-HG), triggering epigenetic reprogramming and blockade of cell differentiation, which are particularly prominent in gliomas and hematological malignancies