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Only a confirmed deficiency should lead to a prescription for B12 injections

Behaviour 132 , 2147 (1995)

receives funding from Novo Nordisk and has received speaking fees from Novo Nordisk, Eli Lilly, Boehringer Ingelheim, Merck, AstraZeneca, Mercodia and Berlin Chemie AG

This targeting strategy thus depends on altered physiological conditions in infected regions rather than ligand-receptor interactions (active targeting) [201, 202]

Additional exclusion factors included uncontrolled diabetes, active genitourinary skin infection, a history of recurrent or active urinary tract infection, non-compliance with pre- or post-operative instructions, and smoking habits that could not be ceased 2 weeks pre- and at least 6 weeks post-surgery as required