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In addition, another study showed that niacin treatment increased HDL cholesterol efflux from macrophage foam cells and inhibited inflammatory responses induced by toll-like receptor 4 (Yvan-Charvet et al., 2010

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1993, Edwards 1996, Eshdat et al

The requirement for Ni in urease has been suggested to account for the essential role of this element in plant physiology, but Ni may also be a cofactor for glyoxalase I, important in the degradation of the toxic metabolite methylglyoxal (Fabiano et al., 2015)