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LA is a unique antioxidant that is not only effective in affording protection against oxidative stress but also plays an essential role in the metabolic processes of all living organisms 36

3.3 Age-associated changes in circadian rhythms Age-associated circadian desynchrony has been shown to negatively impact metabolic function, contributing to increased oxidative stress and impaired sleep

green: ADCY10, red: Bio-OLCarn

In the other study, when cucumber plants exposed to high temperature (30C at night and 38C during the day for consecutive 12 h), identified in total 125 metabolites (26 downregulated and 99 upregulated) that changed under heat stress

Redox equilibrium in mitochondria is maintained primarily by manganese superoxide dismutase (Mn-SOD, SOD2), which is localized in the mitochondrial matrix and rapidly dismutates O 2 to H 2 O 2