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In contrast to earlier results, the researchers concluded that lithium carbonate does not slow the rate of decline of function in patients with ALS, as compared to a control group, and the lithium-treated patients showed no differences in quality of life and were more prone to adverse events (Miller et al., 2011)

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AHCC, a compound derived from the family of fungi to which the shiitake mushroom belongs, has immune-modulating properties and has been shown to be well-tolerated in human study subjects (Spierings 2007)