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Together, these data indicate that blocking the combined phosphorylation of ArfGAP1 at Ser284, T291 and T292 (3A mutant), but not at single sites, impairs neurite outgrowth inhibition consistent with reducing ArfGAP1 activity

This relationship is highlighted in neurological disorders, as they are typically accompanied by gastrointestinal symptoms like abdominal pain, inflammation, and impaired gastric motility[18]

5-HT6 receptor antagonist attenuates the memory deficits associated with neuropathic pain and improves the efficacy of gabapentinoids