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HPLC Analysis STANDARD High-Performance Liquid Chromatography separates peptide components by molecular interaction with a stationary phase

Other factors that could lead to B12 deficiency are: Lack of adequate production of the intrinsic factor needed for B12 absorption B12 deficiency is common in elderly people as absorption of the vitamin reduces with age People who have had any intestinal surgery, such as that for weight loss Those with gut conditions such as Crohn's Disease, inflammatory bowel disease, or celiac disease SLIDESHOW See Slideshow Vitamin B12 injections Vitamin B12 supplements are given based on the condition that causes deficiency

Development was ultimately discontinued after clinical results did not demonstrate sufficient efficacy to meet pharmaceutical thresholds

Neither approach shows a meaningful difference in outcomes