Drug displaced from plasma protein will of course distribute throughout the volume of distribution, so that a 5% increase in the amount of unbound drug in the body produces at most a 5% increase in pharmacologically active unbound drug at the site of action
This condition is rare but has been reported in several breeds, including: Border Collies Beagles Chinese Shar-Peis Giant Schnauzers Australian Shepherds Treatment of cobalamin deficiency When left untreated, cobalamin deficiency can potentially lead to serious health problems
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Vitamin B12 plays a vital role in red blood cell production, nerve function, and cellular energy
In fact according to the NHS the only reliable vegan B12 sources include fortified products, such as: fortified breakfast cereals unsweetened soya drinks that have been fortified with B12 yeast extract, such as Marmite, fortified with B12 It was recently suggested that algae foods have a relatively high vitamin B12 content