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168 This strategy exploits the acidic pH of the tumor milieu to enable selective insertion and delivery, thereby enhancing targeting precision

It is a synthetic peptide derived from Body Protection Compound, a protein found in gastric juice

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Moreover, in cases of nerve pain caused by carpal tunnel syndrome and pain associated with knee osteoarthritis, PEA has demonstrated the ability to reduce neuropathic pain and attenuate symptoms in double-blind, placebo-controlled studies

Angiogenesis experiments use tube formation assays in human umbilical vein endothelial cells (HUVECs), matrigel plug assays in mice, and VEGF protein quantification via Western blot to characterize BPC-157's vascular effects