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Notably, endogenous cellular clocks drive the rhythmic expression of genes

Ethics declarations Competing interests J.M.R has been a paid consultant to Aquestive Pharmaceuticals, Danone Nutricia, Mallinckrodt, Eisai Pharma and Zogenix, and has served on the Scientific Advisory Board of The Charlie Foundation for Ketogenic Therapies (Santa Monica, CA, USA)

The hexamethylenetetramine (HMT, 99.0%), nickel chloride hexahydrate (NiCl 2 6H 2 O), and cobalt chloride hexahydrate (CoCl 2 6H 2 O) were sourced from Aladdin Reagents (Shanghai, China)

Worldwide trends in diabetes prevalence and treatment from 1990 to 2022: a pooled analysis of 1108 population-representative studies with 141 million participants