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Antioxidant activity of carotenoids: An electron-spin resonance study on -carotene and lutein interaction with free radicals generated in a chemical system

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Astrocytic urea cycle detoxifies Abeta-derived ammonia while impairing memory in Alzheimers disease

The increased Bax/Bcl-2 ratio promotes mitochondrial outer membrane permeabilization and cytochrome c release, leading to the activation of caspase-9 and downstream executioner caspase-3 (78)

However, this may change dramatically under some conditions, e.g., in patients with high-dose methotrexate therapy, an anticancer drug that, by inhibiting dihydrofolate reductase, inhibits the tetrahydrofolate-catalyzed recycling of methionine from homocysteine