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GLP-1 receptors are expressed in the hypothalamus, the brainstem, and other central nervous system regions that regulate autonomic tone

Their commendable safety profiles and compatibility with current antidepressant modalities further emphasize their potential contributions to personalized, integrative mental health care

Naqash AR, Ricciuti B, and Owen DH, et al (2020) Outcomes associated with immune-related adverse events in metastatic non-small cell lung cancer treated with nivolumab: a pooled exploratory analysis from a global cohort Cancer Immunol Immunother 69 (7) 11771187 PMID: 32140762 51

Double-strand DNA sensing Aim2 inflammasome regulates atherosclerotic plaque vulnerability

While the most common underlying comorbidities are reported to be obesity, hypertension, diabetes, underlying cardiovascular and lung disease, people with immune-mediated diseases such as autoimmune disease, and those on immune-suppresants or immune-modulating drugs may also be more vulnerable to this infection