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Structure of the human genomic glutathione S-transferase-pi gene

Despite these findings, the use of antioxidants (vitamin E, N-acetylcysteine, coenzyme Q, and others) in patients with alcoholic liver disease has failed to show an efficacy in improving disease conditions [3638]

Among the key causative agents, anthracyclines, such as doxorubicin (DOX), are particularly notable, as the severe cardiac damage they inducecharacterized by ventricular dilatation, interstitial fibrosis, and progression to HFsignificantly limits their clinical utility [73]

This process supports enhanced fat metabolism, energy levels, and cellular repair, particularly within muscle and fat tissue

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