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Sure enough, a popular sports medicine site confirms: Athletes with sickle cell trait are potentially more vulnerable to other serious conditions such as gross hematuria, splenic infarction, exertional heat stroke, severe muscle breakdown (rhabdomyolysis) and potentially even sudden death when participating in strenuous exercise under intense environmental conditions. Short of these devastating problems, which occur rarely with just the trait, more common symptoms may include muscle cramping/pain

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Alpha-lipoic acid is generally considered safe with little to no side effects

Superoxide dismutase catalyzes the conversion of superoxide radicals into hydrogen peroxide, which is then broken down by catalase and GPx into water and oxygen, thereby preventing the accumulation of toxic byproducts and preserving the structural and functional integrity of sperm cells

It also delays the development of the illness and cuts down the hazard of complications [7,8,9]