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The study was a randomized, double-blind, placebo-controlled trial carried out at 51 sites in Japan

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The overall disease control rate (defined as minimal response [MR] or better, or stable disease [SD] for 8 weeks) was 37.5% and, notably, was twofold higher in patients with a longer interval between the last daratumumab dose and isatuximab initiation (58.3% with 6-month washout after daratumumab vs