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In contrast, mitofusin 1 (MFN1), a highly conserved outer membrane GTPase, regulates mitochondrial fusion by initiating membrane tethering, docking, and merging between adjacent mitochondria

Rare Diseases and Genetic Disorders Peptide therapeutics have shown particular promise in treating rare diseases where traditional drug development may be economically challenging

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In addition to inducing P450 enzymes, phenobarbital can also induce glutathione S-transferase A1/A2 (rGSTA1/A2)

While PGC-1 agonists suppress NF-B via NADPH synthesis [198] (Fig