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The glutamine metabolism antagonist, JHU083, has been shown to inhibit M.tb replication both in vitro and in vivo, improving survival, reducing lung bacterial burden, and improving lung histopathology

The low-dose GSH group also experienced significant increases in GSH levels, specifically showing a 17% increase in blood and a 29% increase in erythrocytes at six months compared to baseline

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J Biol Chem 289:49194927