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In the transformation of hemorrhage after cerebral ischemia, iron overload significantly decreases oxidation metabolism, lactic acid generation, and brain pH value, further increasing iron release

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Development 141 , 526537 (2014)

For example, although the relationship between P53 and ferroptosis has been well established[88, 211, 212], there is no evidence suggesting that its methylation is involved in the regulatory effect of P53 on ferroptosis

Evidence for vitamin E/K and minerals such as iron, calcium, and magnesium remains weak or very low, with insufficient human data