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Practical Considerations for Use Start Low, Adjust Gradually Begin with lower doses and increase based on research outcomes

In fact, adenosine acting through microglial A 2A receptors potentiates nitric oxide release [484], and in PD models, A 2A receptor antagonists reduce neuroinflammation by suppressing microglial activation and pro-inflammatory cytokine production, contributing to neuronal survival

The cells were then washed with PBS, and GSH and GSSG levels were determined by applying the GSH/GSSG-Glo assay according to manufacturer instructions

Measures and Assessments The following laboratory markers were analyzed before and after treatment: Plasma reduced glutathione Plasma oxidized glutathione Whole-blood glutathione Plasma cysteine Plasma taurine Plasma sulfate (total and free) All samples were collected under fasting conditions and analyzed at CLIA-certified labs