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However, GPNAs high toxicity of GPNA limits its use in cellular experiments, and the mechanism of V-9302 inhibition is controversial and requires further investigation [80]

The difference between macrophage alone compared to macrophage incubated with primed/unprimed PBMCs in wild-type and BacA groups suggests that BacA induce adaptive immune responses that are efficient in not only clearing the mutant strain from tissue but also decrease the survival of wild-type MAP in macrophages

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Bloating is usually associated with indigestion, gas, and excess acid formation leading to acid reflux