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I read it in a Techoid link, I think

Therefore, although some oligonucleotide products targeting NNMT have shown effectiveness in vitro and in animal experiments, to date, no oligonucleotide products targeting NNMT have been used in clinical trials

Furthermore, Hydroxocobalamin should be used with caution in patients with a history of hypersensitivity to cobalt or cobalt-containing compounds, as it may cause an allergic reaction

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