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The exact receptor of parasites cystatins and their effects on cell signaling are unclear

Although lncRNAs do not encode proteins, they are critical in gene expression regulation, chromatin modification, and post-transcriptional control

Supporting this interpretation, a previous clinical study reported that individuals carrying SNPs associated with reduced GLUT2 expression exhibit greater responsiveness to metformin, further suggesting that decreased intestinal glucose absorption mediated by reduced expression of glucose transporters such as GLUT2 may play an important role in enhancing overall glucose homeostasis after metformin administration 52

Marraccini, T

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