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In the context of CVD risk reduction, the regulation of amino acid metabolism has gained prominence as an important research focus, primarily involving two main strategies: Dietary intervention and pharmacotherapy

The core direction of future research should focus on directly verifying the causal relationship between local joint ferroptosis and gut microbiota dysbiosis through germ-free OA mouse models, fecal microbiota transplantation experiments, or conditional knockout models of key genes for chondrocyte-specific ferroptosis (such as GPX4 and ACSL4)

Furthermore, long-term follow-up studies have demonstrated their safety, efficacy, and diverse therapeutic benefits

It's important to note, however, that not all Parkinson's patients may be suitable for glutathione treatment, and other treatment options may be necessary

In addition, drugs targeting glucose metabolism have the potential to be used for PD treatment, but there are few studies on the treatment of glucose metabolism impairment in PD patients