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I usually notice an uptick in my energy levels a few days after my doc gives the shot." Zoe Macfarlane, 43, Los Angeles Try it: Needles bypass the gut to deliver the nutrient straight to the muscle, so you may feel the effects as soon as the "juice" goes in or up to a few days after

However, individual B12 or iron supplement use during chemotherapy may be significantly associated with poorer outcomes (63)

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