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Gastroenterology 128, 541551

Elevated LC3 and p62 levels in the kidneys of patients with diabetic nephropathy and diabetic rats indicate autophagy dysregulation

Projections suggest a continued escalation, with an estimated prevalence of 7,079 out of 100,000 individuals by 2030, underscoring the growing public health concern [1]

While current research predominantly focuses on mTORC1, mTORC2 deficiency could impair goblet cell mucin secretion via mTORC2-mediated FoxO1 to exacerbate microbial dysbiosis